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The University of Calgary Non-invasive Neurostimulation Network: N3

Neurostimulation Research Program centered on the use of Transcranial Magnetic Stimulation technology.

Transcranial Magnetic Stimulation (TMS), guided by magnetic resonance imaging (MRI), uses a magnetic field to non-­invasively stimulate small targeted regions of the brain. The magnetic coil produces small electric currents in the region of the brain just under the coil via electromagnetic induction. TMS provides an individualized approach to treat disorders, targeting specific brain regions in the context of a patient’s unique neurological or psychiatric symptoms.

For example, TMS is being used by HBI members in studies of Parkinson’s disease to test new therapies that improve patient outcomes and quality of life. This is just one of many cutting-edge clinical research applications of TMS.

The Research Power of N3

N3 is one of the NeuroTechnology platforms that supports the University of Calgary's Brain and Mental Health research strategy.

The goal of the N3: Non-invasive Neurostimulation Network is to build a supportive community of brain and mental health researchers across the University of Calgary. Together, these researchers are undertaking collaborative, interdisciplinary research projects utilizing non-­invasive neurostimulation technologies, to both better understand brain disorders across the lifespan, and modulate neural function toward better health outcomes.

Combining TMS with other non-invasive neurostimulation technologies, N3 will apply these technologies to a university-wide research program that includes the following themes:

  • Movement disorders
  • Mental health
  • Cerebral palsy and neurodevelopmental disorders
  • Neurorehabilitation
  • Pediatric traumatic brain injury and concussion
  • Pain
  • Neuromuscular fatigue

For more information, or to become involved with the N3 network contact the program's leader, Dr. Adam Kirton.

N3 Partnerships

The N3 research program will build upon existing strengths at the University of Calgary, centered in the Cumming School of Medicine and aligned with multiple key internal and external partners including:

  • Hotchkiss Brain Institute (HBI)
  • Alberta Children’s Hospital Research Institute (ACHRI)
  • Cumming School of Medicine
  • Department of Psychiatry
  • Faculty of Kinesiology
  • The Mathison Centre for Mental Health Research & Education
  • Owerko Centre
  • Seaman Family MR Research Centre
  • Integrated Concussion Research Program
  • Child and Adolescent Imaging Research Program
  • Alberta Health Services

N3 Leadership

Program Leader: Dr. Adam Kirton

Dr. Kirton (centre) is a pediatric neurologist and clinician-­scientist based at the Alberta Children’s Hospital. He leads the Calgary Pediatric Stroke Program research team, which runs the university’s most established non-­invasive neurostimulation clinical research program, and is a member of ACHRI and the HBI.

Co-­leaders:

Dr. Oury Monchi

Dr. Monchi (right) is the Tourmaline Oil Chair in Parkinson’s Disease, Research Director of the Cumming School of Medicine’s Movement Disorders Program and a member of the HBI. He currently leads clinical neuroscience investigations using non-­invasive neurostimulation at the Foothills campus. Dr. Monchi is also a leader of the Movement Disorders NeuroTeam that will be an integral part of the N3 network.

Dr. Frank MacMaster

Dr. MacMaster (left) is the Scientific Director of the Addictions and Mental Health Strategic Clinical Network of Alberta Health Services and a member of the HBI, The Mathison Centre for Mental Health Research & Education, and ACHRI. He leads the university’s research intonon-invasive neurostimulation applications for mental health in children and young adults.