A painted illustration shows five diverse people in the foreground, representing mental health conditions across communities, with a central person representing hope. A large, bright pink brain with yellow and pink swirls is in the background.

About MIST

Understanding physical trauma and mental health

Innovative research

By advancing important transdisciplinary research to understand the effects of stress and trauma on the brain and mental health, scientists can develop new treatments.

Education & awareness

By leading community outreach programs we can share this research broadly and help educate and empower people to take action with their own mental health.

Community engagement

By actively involving the community in our research and initiatives, we can work towards advancing innovative interventions and fostering healthier outcomes. Together.

The Mental Health Initiative for Stress and Trauma (MIST) is uncovering mysteries of the brain that surround the interplay between major depression, post-traumatic stress disorder, and post-concussion syndrome. By promoting the advancement of this research along with seeking effective prevention strategies and treatments, MIST is improving outcomes for individuals living at the intersection of brain trauma and mental health challenges. MIST aims to build awareness and deepen research to improve outcomes of, and access to, improved mental health here and around the world.

A clinician is holding an MRI film showing various views of a brain.

Mike McClay skiing with his two young kids on a mountain top, and all stopped to pose for a picture.

The legacy of Mike McClay

Learn about the life of Mike McClay, and why his family and friends partnered with UCalgary to honour his life by saving others.

Read Mike McClay’s legacy

Dr. Alex McGirr demonstrates transcranial magnetic stimulation (TMS) on his graduate student, showing a depiction of her brain on a monitor.

World class research

MIST foundational science is discovering fundamental markers and mechanisms for stress and trauma-related mental health conditions, whereas MIST clinical studies are exploring new treatments and solutions for depression, post-concussion syndrome, and post-traumatic stress disorder.

Learn about MIST research

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